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KMID : 0359720160340010037
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Journal of the Korean Neurological Association
2016 Volume.34 No. 1 p.37 ~ p.40
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Usefulness of Extracorporeal Treatment for Combined Intoxication with Controlled-Release Carbamazepine and Topiramate
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김민정:Kim Min-Jung
권오영:Kwon Oh-Young/김도형:Kim Do-Hyung/유상경:Yoo Sang-Kyeong/박동준:Park Dong-Jun/정희정:Jeong Hee-Jeong/손승남:Son Seung-Nam/김수경:Kim Soo-Kyoung/강희영:Kang Hee-Young/박기종:Park Ki-Jong/최낙천:Choi Nack-Cheon/임병훈:Lim Byeong-Hoon
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Abstract
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Controlled-release carbamazepine (CBZ) could be more harmful than the regular form in special situations due to their respective biochemical characteristics. When primary treatment is not effective in acute intoxication, extracorporeal treatment (ECTR) could be an option. We recently applied ECTR to a patient with combined intoxication of topiramate and controlled-release CBZ who deteriorated despite receiving primary treatment. The patient improved after administering ECTR. Early ECTR intervention may be beneficial for the treatment of CBZ intoxication, especially of the controlled-release form.
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KEYWORD
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Carbamazepine, Topiramate, Extracorporeal circulation
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